Rat

LC (Locus ceruleus) projects to CEA (central amygdaloid nucleus)

1 claim from 1 source: 1 found, 0 tested and absent, 0 ambiguous. Evidence: retrograde tracer.

The claims behind it

clm-q6qrn51949presentretrograde tracerproposed

Fluorescent dextran injected into CeA retrogradely labelled neurons throughout the dorsoventral extent of LC, with a bias toward the dorsal part; in the same animals only about 7.6% of all labelled LC cells carried both the CeA and mPFC tracers, indicating largely separate populations. A retrogradely transported CAV2 vector with a noradrenergic-selective PRS promoter injected into CeA also transduced LC neurons, confirming the pathway arises from noradrenergic LC cells.

DOI 10.1016/j.ynstr.2020.100284 · PubMed 33344735 · PMC7739179, Fig. 1E, 1G, 1H; Fig. 3A,C; Methods (Surgery)

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