Rat

LC (Locus ceruleus) projects to PL (Prelimbic area)

1 claim from 1 source: 1 found, 0 tested and absent, 0 ambiguous. Evidence: retrograde tracer.

The claims behind it

clm-n8jrgnwggrpresentretrograde tracerproposed

Fluorescent dextran injected at the border of prelimbic and infralimbic cortex retrogradely labelled LC neurons, in numbers statistically indistinguishable from those labelled from CeA, and these cells were largely distinct from the CeA-projecting population (~7.6% double-labelled). A retrogradely transported noradrenergic-selective CAV2-PRS-Cre vector injected into mPFC likewise transduced LC neurons.

DOI 10.1016/j.ynstr.2020.100284 · PubMed 33344735 · PMC7739179, Fig. 1E, 1G, 1I; Fig. 3B,D; Methods (Surgery)

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