Rat

CEA (central amygdaloid nucleus) functionally connects to PAG (Periaqueductal gray)

1 claim from 1 source: 1 found, 0 tested and absent, 0 ambiguous. Evidence: optogenetic circuit mapping.

The claims behind it

clm-07rvxvy8stpresentoptogenetic circuit mappingproposed

CeA ChR2 stimulation was associated with lower Fos in ventrolateral periaqueductal gray: more than 200% reduction below normal tissue baseline in reward-pursuing rats, and markedly lower counts than in eYFP controls (which showed over 400% elevation) in the shock-rod situation, so CeA activation changed PAG activity in the negative direction.

DOI 10.1038/s41467-020-16407-1 · PubMed 32483118 · PMC7264246, Results, 'Shock-rod attraction activates mesocorticolimbic circuity'; Fig. 5; Supplementary Table 1

Made by an AI model reading the paper (claude-opus-5, extract@0.3.0); a second AI model (claude-opus-5) agrees.