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Rat

CEA (central amygdaloid nucleus) projects to PB (Parabrachial nucleus)

2 claims from 1 source: 2 found, 0 tested and absent, 0 ambiguous. Evidence: anterograde tracer.

The claims behind it

clm-kj41qyrdw7presentanterograde tracerproposed

Cre-dependent synaptophysin-mRuby expressed in GAD1-positive central amygdala neurons of Gad1-iCre rats produced red synaptophysin puncta in the lateral parabrachial nucleus, where they colocalized with CaMKIIa-EGFP-labelled excitable neurons across serial optical z-sections; puncta per CaMKIIa cell and the number of CaMKIIa cells bearing puncta were reduced by Nrxn3 knockdown in the central amygdala and puncta number was increased by whisker-pad VZV injection.

DOI 10.2147/jpr.s441706 · PubMed 38974829 · PMC11227312, Figs. 4C–N, 5A–R

Made by an AI model reading the paper (claude-opus-5, extract@0.3.0); a second AI model (claude-opus-5) agrees.

clm-pfjqhrb3vtpresentanterograde tracerproposed

Synaptophysin-mRuby terminals from GAD1-positive central amygdala neurons were found on lateral parabrachial cells that were both CaMKIIa-EGFP positive and immunoreactive for prodynorphin; the number of such prodynorphin/EGFP cells contacted by synaptophysin puncta fell after Nrxn3 knockdown in the central amygdala.

DOI 10.2147/jpr.s441706 · PubMed 38974829 · PMC11227312, Figs. 6D–I

Made by an AI model reading the paper (claude-opus-5, extract@0.3.0); a second AI model (claude-opus-5) agrees.