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PGRN (Paragigantocellular reticular nucleus) projects to LC (Locus ceruleus)

1 claim from 1 source: 1 found, 0 tested and absent, 0 ambiguous. Evidence: retrograde tracer.

The claims behind it

clm-re8d1g14evpresentretrograde tracerproposed

Iontophoretic Fluorogold injections into the LC core and dorsolateral peri-LC consistently labeled cell bodies in the PGi in every case. Some of these retrogradely labeled PGi cells were enkephalin-immunoreactive.

DOI 10.1523/eneuro.0042-15.2015 · PubMed 26634226 · PMC4660134, Results, 'Repeated stress and retrograde labeling'; Fig. 1B; Fig. 2

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.