Rat

PL (Prelimbic area) functionally connects to ACB (Nucleus accumbens)

1 claim from 1 source: 1 found, 0 tested and absent, 0 ambiguous. Evidence: optogenetic circuit mapping.

The claims behind it

clm-a59nmx9e4ypresentoptogenetic circuit mappingproposed

ChR2 was expressed in PL under a CaMKIIα promoter and an optic fiber was placed over PL axon terminals in ventral striatum; blue-light stimulation at 4 Hz and 15 Hz of these terminals reduced platform-mediated avoidance in a frequency-dependent way, indicating a functional PL axonal input to ventral striatum. Photosilencing the same terminals with ArchT had no detectable behavioral effect.

DOI 10.7554/elife.59281 · PubMed 33054975 · PMC7588229, Fig. 1B-E; Results, 'PL projections to the VS'

Made by an AI model reading the paper (claude-opus-5, extract@0.3.0); a second AI model (claude-opus-5) agrees.