Skip to content

Rat

PL (Prelimbic area) functionally connects to BLA (basal amygdaloid nucleus)

1 claim from 1 source: 1 found, 0 tested and absent, 0 ambiguous. Evidence: optogenetic circuit mapping.

The claims behind it

clm-6zchqnnfkspresentoptogenetic circuit mappingproposed

With ChR2 driven by the CaMKIIα promoter in PL and fibers over PL terminals in BLA, 15 Hz illumination increased avoidance and reinstated it after extinction, while ArchT-mediated silencing of the same PL terminals in BLA impaired avoidance; the authors treat this as a necessary excitatory PL-to-BLA pathway.

DOI 10.7554/elife.59281 · PubMed 33054975 · PMC7588229, Fig. 2A-H; Results, 'PL projections to the BLA'

Made by an AI model reading the paper (claude-opus-5, extract@0.3.0); a second AI model (claude-opus-5) agrees.