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ILA (Infralimbic area) functionally connects to CEA (central amygdaloid nucleus)

1 claim from 1 source: 1 found, 0 tested and absent, 0 ambiguous. Evidence: optogenetic circuit mapping.

The claims behind it

clm-8mh25qv6x9presentoptogenetic circuit mappingproposed

Blue-light stimulation of ChR2-expressing IL terminals in amygdala slices evoked EPSCs in CeLC neurons that disappeared with TTX, were restored by 4-AP and abolished by CNQX, indicating a monosynaptic glutamatergic input; the same stimulation also produced longer-latency, CNQX- and picrotoxin-sensitive IPSCs, consistent with disynaptic feed-forward inhibition, and in vivo photostimulation of these terminals lowered c-Fos counts in CeLC.

DOI 10.1177/17448069241226960 · PubMed 38172075 · PMC10851759, Fig. 3(c)-(e), Fig. 4(b)-(d), Fig. 5(f), (g)

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