ILA (Infralimbic area) functionally connects to Rat basal amygdaloid nucleus principal neurons

Optical stimulation of ventral mPFC terminals evoked GABAergic IPSCs in BLA principal neurons with longer latencies than the EPSCs; these IPSCs were attenuated by picrotoxin and by DNQX, consistent with recruitment of local GABAergic neurons rather than direct inhibition.

Made by an AI model reading the paper (claude-opus-5, extract@0.3.0); a second AI model (claude-opus-5) disagrees. “The IPSCs are DNQX-sensitive local circuit responses, so the vmPFC input itself is not inhibitory as the sign asserts.”

Optical stimulation of ventral mPFC ChR2-expressing terminals produced EPSCs in BLA principal neurons that persisted in TTX plus 4-AP (about 81% of baseline amplitude, i.e. largely monosynaptic) and were eliminated by DNQX, showing glutamatergic input.

Made by an AI model reading the paper (claude-opus-5, extract@0.3.0); a second AI model (claude-opus-5) agrees.