clm-mfvmm5pdz9

ILA (Infralimbic area) functionally connects to Rat basal amygdaloid nucleus principal neurons

Species: Rat
Result: present
Method: optogenetic circuit mapping
Sign: inhibitory
Evidence: Optical stimulation of ventral mPFC terminals evoked GABAergic IPSCs in BLA principal neurons with longer latencies than the EPSCs; these IPSCs were attenuated by picrotoxin and by DNQX, consistent with recruitment of local GABAergic neurons rather than direct inhibition.
Measurements: conduction delay: 18.8 ms (SEM 1.1), n = 13
conduction delay: 21.7 ms (SEM 1.2), n = 13
Source: Chronic Ethanol Differentially Modulates Glutamate Release from Dorsal and Ventral Prefrontal Cortical Inputs onto Rat Basolateral Amygdala Principal Neurons
eneuro, 2019
DOI 10.1523/eneuro.0132-19.2019 · PubMed 31548367 · PMC7070451, Fig. 6B3, B4
Licence: CC-BY-NC-SA-4.0
Named in the paper: “vmPFC” and “BLA principal neurons”
Made by: an AI model reading the paper (claude-opus-5, extract@0.3.0), 2026-10-10
Checked by: a second AI model (claude-opus-5) disagrees, 2026-10-10
“The IPSCs are DNQX-sensitive local circuit responses, so the vmPFC input itself is not inhibitory as the sign asserts.”
Status: proposed
Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.