Mouse

BLA parvalbumin-expressing interneurons functionally connects to BLA (Basolateral amygdalar nucleus)

1 claim from 1 source: 1 found, 0 tested and absent, 0 ambiguous. Evidence: optogenetic circuit mapping.

The claims behind it

clm-0dcxk68jxfpresentoptogenetic circuit mappingproposed

Optogenetic activation of channelrhodopsin-expressing parvalbumin interneurons in the BLA, with light pulses or sinusoidal waveforms, produced both light-suppressed and light-activated single units in the same nucleus in vivo; the authors interpret the suppression as rapid synaptic inhibition of surrounding BLA neurons, with some cells showing rebound spiking. Spiking of BLA units became entrained to the phase of the 4 Hz and 8 Hz light waveforms.

DOI 10.1038/s41467-020-18199-w · PubMed 32868768 · PMC7459312, Fig. 3b–c; Supplementary Fig. 1h–k; Fig. 3d–m

Made by an AI model reading the paper (claude-opus-5, extract@0.3.0); a second AI model (claude-opus-5) agrees.