clm-0dcxk68jxf

BLA parvalbumin-expressing interneurons functionally connects to BLA (Basolateral amygdalar nucleus)

Species: Mouse
Result: present
Method: optogenetic circuit mapping
Sign: inhibitory
Evidence: Optogenetic activation of channelrhodopsin-expressing parvalbumin interneurons in the BLA, with light pulses or sinusoidal waveforms, produced both light-suppressed and light-activated single units in the same nucleus in vivo; the authors interpret the suppression as rapid synaptic inhibition of surrounding BLA neurons, with some cells showing rebound spiking. Spiking of BLA units became entrained to the phase of the 4 Hz and 8 Hz light waveforms.
Measurements: connection probability: 0.348, n = 66
connection probability: 0.303, n = 66
Source: Experience-dependent resonance in amygdalo-cortical circuits supports fear memory retrieval following extinction
Nature Communications, 2020
DOI 10.1038/s41467-020-18199-w · PubMed 32868768 · PMC7459312, Fig. 3b–c; Supplementary Fig. 1h–k; Fig. 3d–m
Licence: CC-BY-4.0
Named in the paper: “BLA PV-interneurons” and “BLA”
Made by: an AI model reading the paper (claude-opus-5, extract@0.3.0), 2026-10-09
Checked by: a second AI model (claude-opus-5) agrees, 2026-10-09
“In vivo optogenetic driving of BLA PV cells produced light-suppressed BLA units and phase-locking of 23/66 (34.8%) and 20/66 (30.3%) units to the 4 Hz and 8 Hz waveforms, matching the cited values and locators.”
Status: proposed
Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.