Mouse

BLA parvalbumin-expressing interneurons functionally connects to LA glutamatergic principal neurons

1 claim from 1 source: 1 found, 0 tested and absent, 0 ambiguous. Evidence: optogenetic circuit mapping.

The claims behind it

clm-frktq2k1w9presentoptogenetic circuit mappingproposed

After Cre-dependent ChR2 expression in parvalbumin interneurons of the basolateral amygdala, blue-light pulses evoked inhibitory postsynaptic currents in lateral amygdala principal neurons recorded with glutamate receptor blockers present; paired-pulse ratios differed between genotypes, indicating a lower GABA release probability when Mecp2 was deleted from the PV cells.

DOI 10.1186/s13229-025-00699-5 · PubMed 41491494 · PMC12829049, Fig. 1b; Results, section on PV output

Made by an AI model reading the paper (claude-opus-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.