Mouse

CEA corticotropin-releasing hormone-expressing neurons functionally connects to CP (Caudoputamen)

1 claim from 1 source: 1 found, 0 tested and absent, 0 ambiguous. Evidence: optogenetic circuit mapping.

The claims behind it

clm-jgkwagd7ewpresentoptogenetic circuit mappingproposed

AAV-FLEX-Chrimson-tdTomato was injected into both CeA and BNST of CRF-Cre;ChAT-eGFP mice; light stimulation of the labelled fibres in dorsal striatum evoked short-latency synaptic currents in GFP+ cholinergic interneurons that were abolished by TTX, restored by TTX+4-AP (indicating monosynaptic transmission) and blocked by the GABA-A antagonist bicuculline.

DOI 10.7554/elife.107145 · PubMed 41870239 · PMC13008356, Fig. 3G–3J

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