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BLA glutamatergic principal neurons functionally connects to CA3 (Field CA3)

1 claim from 1 source: 1 found, 0 tested and absent, 0 ambiguous. Evidence: optogenetic circuit mapping.

The claims behind it

clm-13s11tn7g6presentoptogenetic circuit mappingproposed

After expressing ChR2 under the CaMKIIα promoter in BLA, blue light evoked EPSCs in dCA3 neurons recorded in slices; the responses persisted with TTX and 4-AP (monosynaptic) and were abolished by the AMPA receptor blocker DNQX, indicating a direct glutamatergic BLA-to-dCA3 connection.

DOI 10.1016/j.ebiom.2026.106478 · PubMed 42700720 · PMC13572171, Fig. 1J–L

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