BLA glutamatergic principal neurons functionally connects to CEA (Central amygdalar nucleus)

Cre-dependent ChR2 was expressed in BLA excitatory neurons of CaMKII-Cre mice; blue-light stimulation of their terminals in the CeA elicited EPSCs in CeA neurons that were abolished by the AMPA receptor blocker DNQX, indicating a glutamatergic BLA-to-CeA input. These light-evoked EPSCs were suppressed by the DOR1 agonist DPDPE in normal and 4-h CFA mice but by neither DPDPE nor deltorphin II in 7-day CFA mice.

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