Central amygdalar PKCδ neurons mediate fentanyl withdrawal

COA (Cortical amygdalar area) MBA:631 synapses onto CEAl PKC-delta-expressing neurons nt-g513b58b0y · Mouse

Rabies tracing from CeLC PKCδ starter cells labelled input neurons in the cortical amygdala.

Fig. 5c, 5e

Made by an AI model reading the paper (claude-opus-5, extract@0.3.0); a second AI model (claude-opus-5) agrees.

CP (Caudoputamen) MBA:672 projects to CEA (Central amygdalar nucleus) MBA:536 · Mouse

A retrogradely transported colour-switching AAV injected into the right CeA of Oprm1-Cre mice labelled many caudate-putamen neurons (28119 cells counted), 66% of which were Oprm1-positive.

Fig. 5d, 5e

Made by an AI model reading the paper (claude-opus-5, extract@0.3.0); a second AI model (claude-opus-5) agrees.

BMA (Basomedial amygdalar nucleus) MBA:319 synapses onto CEAl PKC-delta-expressing neurons nt-g513b58b0y · Mouse

Monosynaptic rabies tracing from CeLC PKCδ neurons labelled presynaptic neurons in the basomedial amygdala.

Fig. 5c, 5e

Made by an AI model reading the paper (claude-opus-5, extract@0.3.0); a second AI model (claude-opus-5) agrees.

STR (Striatum) MBA:477 synapses onto CEAl PKC-delta-expressing neurons nt-g513b58b0y · Mouse

Monosynaptic rabies tracing from CeLC PKCδ neurons labelled presynaptic cells in the amygdalostriatal transition area, part of the dense striatal input.

Fig. 5c, 5e

Made by an AI model reading the paper (claude-opus-5, extract@0.3.0); a second AI model (claude-opus-5) disagrees. “The subject ID is the whole striatum rather than the amygdalostriatal transition area named in the paper.”

BST (Bed nuclei of the stria terminalis) MBA:351 projects to CEA (Central amygdalar nucleus) MBA:536 · Mouse

Retrograde colour-switching AAV from the CeA labelled 1472 BNST neurons, 73% Oprm1-positive.

Fig. 5e

Made by an AI model reading the paper (claude-opus-5, extract@0.3.0); a second AI model (claude-opus-5) agrees.

SI (Substantia innominata) MBA:342 projects to CEA (Central amygdalar nucleus) MBA:536 · Mouse

Retrograde AAV from the CeA labelled 1171 substantia innominata neurons, 67% Oprm1-positive.

Fig. 5e

Made by an AI model reading the paper (claude-opus-5, extract@0.3.0); a second AI model (claude-opus-5) agrees.

PVT (Paraventricular nucleus of the thalamus) MBA:149 projects to CEA (Central amygdalar nucleus) MBA:536 · Mouse

Retrograde AAV from the CeA labelled 3968 paraventricular thalamic neurons, 75% Oprm1-positive.

Fig. 5e

Made by an AI model reading the paper (claude-opus-5, extract@0.3.0); a second AI model (claude-opus-5) agrees.