clm-11jnzehsmx

PL (Prelimbic area) projects to ACB (Nucleus accumbens)

Species: Mouse
Result: present
Method: retrograde tracer
Sign: unknown
Evidence: Retrograde AAV expressing Cre-GFP was injected into the nucleus accumbens with a Cre-dependent Gi-DREADD-mCherry vector in prelimbic cortex; co-labelled Cre+/mCherry+ neurons in PL demonstrate a prelimbic projection to the accumbens.
Source: Social incentivization of instrumental choice in mice requires amygdala-prelimbic cortex-nucleus accumbens connectivity
Nature Communications, 2022
DOI 10.1038/s41467-022-32388-9 · PubMed 35970891 · PMC9378688, Fig. 5e (right panel); Methods, Table 2
Licence: CC-BY-4.0
Named in the paper: “PL” and “NAc”
Made by: an AI model reading the paper (claude-opus-5, extract@0.3.0), 2026-10-09
Checked by: a second AI model (claude-opus-5-5) agrees, 2026-10-09
“Retrograde Cre-GFP in NAc with Cre-dependent mCherry-DREADD expression in PL neurons, shown in Fig. 5e right, supports a PL-to-NAc projection in mice.”
Status: proposed
Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.