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BLA (Basolateral amygdalar nucleus) functionally connects to PL (Prelimbic area)

Species: Mouse
Result: present
Method: optogenetic circuit mapping
Sign: excitatory
Evidence: Optogenetic stimulation of BLA axons evoked EPSCs and IPSCs in L5 PL cortico-PAG neurons; blockers reduced these to a small monosynaptic EPSC and removed the IPSC. L2 PL corticoamygdalar neurons received strong monosynaptic EPSCs and could be driven to fire action potentials.
Source: Specific Targeting of the Basolateral Amygdala to Projectionally Defined Pyramidal Neurons in Prelimbic and Infralimbic Cortex
eneuro, 2016
DOI 10.1523/eneuro.0002-16.2016 · PubMed 27022632 · PMC4804386, Fig. 2H-K; Fig. 3A-D, J-L
Licence: CC-BY-NC-SA-4.0
Named in the paper: “basolateral amygdala (BLA)” and “PL cortex (L5 PL-CP neurons, L2 PL-CA neurons)”
Made by: an AI model reading the paper (claude-opus-5-5, extract@0.3.0), 2026-10-09
Checked by: a second AI model (claude-opus-5-5) agrees, 2026-10-09
“Optogenetic BLA stimulation gave monosynaptic EPSCs in PL-CP and L2 PL-CA neurons and drove PL-CA firing, while IPSCs were removed by the blockers.”
Status: proposed
Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.