clm-bk5853g2tq

PIL (Posterior intralaminar thalamic nucleus) functionally connects to Intercalated cell GABAergic neurons

Species: Mouse
Result: present
Method: optogenetic circuit mapping
Sign: excitatory
Evidence: Blue-light activation of ChR2-expressing thalamic terminals evoked glutamatergic EPSCs in patched medial paracapsular intercalated cells, with AMPA receptor-mediated currents isolated at -70 mV in bicuculline and NMDA receptor-mediated currents isolated with NBQX; responses were graded with light intensity in both genotypes.
Source: Deletion of ErbB4 Disrupts Synaptic Transmission and Long-Term Potentiation of Thalamic Input to Amygdalar Medial Paracapsular Intercalated Cells
Frontiers in Synaptic Neuroscience, 2021
DOI 10.3389/fnsyn.2021.697110 · PubMed 34393751 · PMC8355744, Fig. 2D,E; Fig. 3A,D,E
Licence: CC-BY-4.0
Named in the paper: “PIN/MGm (thalamic fibers)” and “mpITCs”
Made by: an AI model reading the paper (claude-opus-5, extract@0.3.0), 2026-10-10
Checked by: a second AI model (claude-opus-5) agrees, 2026-10-10
“Light activation of thalamic ChR2 terminals evoked AMPA and NMDA EPSCs in mpITCs across intensities (Figs. 2, 3).”
Status: proposed
Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.