clm-bnx1jwbh1c

PB (Parabrachial nucleus) functionally connects to CEA (Central amygdalar nucleus)

Species: Mouse
Result: present
Method: optogenetic circuit mapping
Sign: excitatory
Evidence: Wide-field blue-light stimulation of ChR2-expressing parabrachial axons in TTX plus 4-AP evoked monosynaptic EPSCs in all six central amygdala neurons tested, and these currents were abolished by the AMPA-receptor blocker NBQX; no monosynaptic IPSCs were seen.
Measurements: connection probability: 1, n = 6
Source: Spared nerve injury differentially alters parabrachial monosynaptic excitatory inputs to molecularly specific neurons in distinct subregions of the central amygdala
Pain, 2019
DOI 10.1097/j.pain.0000000000001691 · PubMed 31479066 · PMC6940027, Fig. 2C–E; Results 3.2
Licence: CC-BY-NC-ND-4.0
Named in the paper: “PBn” and “CeA”
Made by: an AI model reading the paper (claude-opus-5, extract@0.3.0), 2026-10-09
Checked by: a second AI model (claude-opus-5-5) agrees, 2026-10-09
“All six CeA neurons showed monosynaptic EPSCs that NBQX blocked, and no IPSCs were evoked.”
Status: proposed
Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.