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PB (Parabrachial nucleus) functionally connects to Rat central amygdala corticotropin-releasing hormone-expressing neurons

All claims for this connection
Species
Rat
Result
present
Method
electrical stimulation
Sign
excitatory
Evidence
Focal electrical stimulation of the PB fiber tract dorsomedial to the CeA evoked glutamate receptor-dependent EPSCs, plus feedforward IPSCs, in all CeA CRF neurons tested in brain slices.
Measurements
  • connection probability: 1, n = 6
Source

Kappa Opioid Receptor Blockade in the Amygdala Mitigates Pain Like-Behaviors by Inhibiting Corticotropin Releasing Factor Neurons in a Rat Model of Functional Pain

Frontiers in Pharmacology, 2022

DOI 10.3389/fphar.2022.903978 · PubMed 35694266 · PMC9177060, Fig. 6F,G; Results 2.4

Licence: CC-BY-4.0

Named in the paper
“parabrachial fibers (PB)” and “CeA-CRF neurons”
Made by
an AI model reading the paper (claude-opus-5-5, extract@0.3.0), 2026-10-10
Checked by

a second AI model (claude-opus-5-5) agrees, 2026-10-10

“Electrical stimulation of PB fibers dorsomedial to the CeA evoked glutamate-dependent EPSCs plus IPSCs in all CRF neurons tested, and the caption reports n = 6 for electrical.”

Status

proposed

Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.