Rat

PB (Parabrachial nucleus) functionally connects to Rat central amygdala corticotropin-releasing hormone-expressing neurons

2 claims from 1 source: 2 found, 0 tested and absent, 0 ambiguous. Evidence: electrical stimulation, optogenetic circuit mapping.

The claims behind it

clm-1nj368jabfpresentoptogenetic circuit mappingproposed

Blue-light activation of ChR2-expressing PB terminals in slices from Crh-Cre rats evoked EPSCs in every mCherry-labelled CeA CRF neuron tested. AP5/CNQX blocked these EPSCs. The same stimulation also evoked glutamate-dependent feedforward IPSCs that bicuculline blocked; yellow light evoked no response.

DOI 10.3389/fphar.2022.903978 · PubMed 35694266 · PMC9177060, Fig. 6D,E; Results 2.4

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.

clm-ccc012ek0ypresentelectrical stimulationproposed

Focal electrical stimulation of the PB fiber tract dorsomedial to the CeA evoked glutamate receptor-dependent EPSCs, plus feedforward IPSCs, in all CeA CRF neurons tested in brain slices.

DOI 10.3389/fphar.2022.903978 · PubMed 35694266 · PMC9177060, Fig. 6F,G; Results 2.4

Made by an AI model reading the paper (claude-opus-5-5, extract@0.3.0); a second AI model (claude-opus-5-5) agrees.