clm-f9zdkg97ba

BLA (Basolateral amygdalar nucleus) functionally connects to Isocortex

Species: Mouse
Result: present
Method: optogenetic circuit mapping
Sign: unknown
Evidence: In slices, light activation of ChR2-expressing BLA axons evoked short-latency, low-jitter EPSCs in FrA L2/3 pyramidal neurons, consistent with a monosynaptic connection. In vivo, photostimulating BLA produced depolarizations in every recorded FrA neuron, although these responses were weak and variable.
Measurements: conduction delay: 3.5 ms (SEM 0.36), n = 9
connection probability: 1, n = 13
Source: The integration of Gaussian noise by long-range amygdala inputs in frontal circuit promotes fear learning in mice
eLife, 2020
DOI 10.7554/elife.62594 · PubMed 33252331 · PMC7704104, Figure 5—figure supplement 1D–G; Fig. 5B,C
Licence: CC-BY-4.0
Named in the paper: “BLA” and “L2/3 FrA pyramidal neurons”
Made by: an AI model reading the paper (claude-opus-5-5, extract@0.3.0), 2026-10-10
Checked by: a second AI model (claude-opus-5-5) agrees, 2026-10-10
“Slice EPSC latency was 3.5 ± 0.36 ms (n = 9) and in vivo BLA photostimulation depolarized all 13 recorded FrA neurons, matching the claim's numbers.”
Status: proposed
Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.