clm-ga36snbkd6

ORB (Orbital area) synapses onto CP (Caudoputamen)

Species: Mouse
Result: present
Method: transsynaptic tracer
Sign: unknown
Evidence: An anterograde transsynaptic AAV1 carrying Cre was placed in the orbitofrontal cortex together with an AAV1-Flpo in the basolateral amygdala and a Cre-dependent/Flp-dependent EYFP reporter in the dorsomedial striatum. EYFP-labelled striatal neurons appeared only when both recombinase viruses were delivered, indicating that orbitofrontal axons transsynaptically label dorsomedial striatal cells, which were then recorded in slices.
Source: Effects of chronic ethanol exposure on dorsal medial striatal neurons receiving convergent inputs from the orbitofrontal cortex and basolateral amygdala
Neuropharmacology, 2025
DOI 10.1016/j.neuropharm.2025.110303 · PubMed 39814131 · PMC12882081, Fig. 1A–B; Results, first paragraph
Licence: CC-BY-NC-ND-4.0
Named in the paper: “OFC” and “DMS”
Made by: an AI model reading the paper (claude-opus-5, extract@0.3.0), 2026-10-09
Checked by: a second AI model (claude-opus-5-5) agrees, 2026-10-09
“OFC AAV1-Cre plus the intersectional DMS reporter labelled DMS neurons in mice, and single-recombinase controls showed no signal (Fig. 1B, first Results paragraph).”
Status: proposed
Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.