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AI (Agranular insular area) projects to BLA (Basolateral amygdalar nucleus)

Species: Mouse
Result: present
Method: anterograde tracer
Sign: unknown
Evidence: After bilateral injection of AAV5-CaMKIIa-eYFP (or eNpHR3.0-eYFP) into the anterior insula, eYFP-labelled axon terminals were found in the basolateral amygdala. Quantification of nine confocal images from a representative animal showed the mean eYFP intensity was significantly greater in BLA than in CeA (paired t-test, t(8) = 8.04, p < 0.001).
Source: The anterior insula and its projection to amygdala nuclei modulate the abstinence-exacerbated expression of conditioned place preference
Psychopharmacology, 2023
DOI 10.1007/s00213-023-06499-0 · PubMed 38010515 · PMC10884150, Fig. 3b, c; Results, aIC-AMY photoinhibition section
Licence: CC-BY-4.0
Named in the paper: “anterior insular cortex (aIC)” and “basolateral nucleus of the amygdala (BLA)”
Made by: an AI model reading the paper (claude-opus-5, extract@0.3.0), 2026-10-09
Checked by: a second AI model (claude-opus-5) agrees, 2026-10-09
“Paper reports eYFP-labelled aIC axons in BLA with the stated paired t-test values from AAV-based anterograde labeling in mice.”
Status: proposed
Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.