clm-gra1nr72vk
BST (Bed nuclei of the stria terminalis) functionally connects to LHA (Lateral hypothalamic area)
All claims for this connection- Species
- Mouse
- Result
- present
- Method
- optogenetic circuit mapping
- Sign
- inhibitory
- Evidence
- After ChR2 was expressed in BNST neurons, blue light stimulation of BNST axons in LHA slices evoked postsynaptic currents in 42 of 70 patched LHA neurons; 36 of those 42 connected cells showed light-evoked IPSCs that persisted with TTX/4-AP (monosynaptic) and were nearly abolished by the GABA-A antagonist gabazine. Connected cells were spread along the anterior–posterior LHA but were most common in middle and posterior LHA.
- Measurements
- connection probability: 0.6, n = 70
- Source
Maternal overnutrition is associated with altered synaptic input to lateral hypothalamic area
Molecular Metabolism, 2023
DOI 10.1016/j.molmet.2023.101702 · PubMed 36898526 · PMC10025284, Fig. 3E–I, Figs. S2E–GLicence: CC-BY-NC-ND-4.0
- Named in the paper
- “BNST” and “LHA”
- Made by
- an AI model reading the paper (claude-opus-5, extract@0.3.0), 2026-10-09
- Checked by
a second AI model (claude-opus-5) agrees, 2026-10-09
“ChR2 mapping showed 42/70 LHA neurons connected, mostly GABAergic IPSCs blocked by gabazine, matching the stated probability and locator.”
- Status
proposed
Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.