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BLA (Basolateral amygdalar nucleus) functionally connects to PL (Prelimbic area)

Species: Mouse
Result: present
Method: optogenetic circuit mapping
Sign: unknown
Evidence: Rhythmic optogenetic driving of BLA parvalbumin interneurons at 4 Hz or 8 Hz shifted not only the BLA local field potential spectrum but also the mPFC spectrum toward the stimulation frequency, and changed the BLA–mPFC cross-power spectrum, indicating that activity imposed in the BLA propagates to and is amplified in mPFC (in a memory-state dependent way for the cross-power measure).
Source: Experience-dependent resonance in amygdalo-cortical circuits supports fear memory retrieval following extinction
Nature Communications, 2020
DOI 10.1038/s41467-020-18199-w · PubMed 32868768 · PMC7459312, Results, 'Effects of BLA stimulation on BLA-mPFC oscillatory activity'; Supplementary Fig. 4d,f; Fig. 5d–i
Licence: CC-BY-4.0
Named in the paper: “BLA” and “mPFC”
Made by: an AI model reading the paper (claude-opus-5, extract@0.3.0), 2026-10-09
Checked by: a second AI model (claude-opus-5) agrees, 2026-10-09
“BLA PV stimulation shifted mPFC LFP power and BLA-mPFC cross-power toward the driven frequency, supporting a functional BLA-to-mPFC (prelimbic coordinates) influence.”
Status: proposed
Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.