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BLA (basal amygdaloid nucleus) functionally connects to PL (Prelimbic area)

Species: Rat
Result: present
Method: optogenetic circuit mapping
Sign: excitatory
Evidence: Optogenetic activation of BLA terminals evoked excitatory currents in mCherry-tagged PrL PV interneurons. The currents included monosynaptic AMPA and APV-sensitive NMDA components and asynchronous EPSCs recorded under TTX/4-AP, and they were reduced by adolescent ethanol exposure.
Source: Adolescent alcohol exposure promotes mechanical allodynia and alters synaptic function at inputs from the basolateral amygdala to the prelimbic cortex
eLife, 2025
DOI 10.7554/elife.101667 · PubMed 40338067 · PMC12061479, Figs. 9-11
Licence: CC-BY-4.0
Named in the paper: “basolateral amygdala (BLA)” and “PrL parvalbumin interneurons (PVINs)”
Made by: an AI model reading the paper (claude-opus-5-5, extract@0.3.0), 2026-10-10
Checked by: a second AI model (claude-opus-5-5) agrees, 2026-10-10
“BLA terminal stimulation evoked monosynaptic AMPA, NMDA and asynchronous EPSCs in PV interneurons, and AIE reduced them (Figs. 9-11).”
Status: proposed
Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.