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PL (Prelimbic area) functionally connects to Rat basal amygdaloid nucleus principal neurons

All claims for this connection
Species
Rat
Result
present
Method
optogenetic circuit mapping
Sign
inhibitory
Evidence
Light activation of dorsal mPFC terminals also evoked GABAergic IPSCs in BLA principal neurons recorded at 0 mV; their onset was much later than the EPSCs and they were blocked by picrotoxin as well as by DNQX, indicating a polysynaptic local inhibitory circuit recruited by this input.
Measurements
  • conduction delay: 23.3 ms (SEM 1.9), n = 7
  • conduction delay: 25.9 ms (SEM 1.6), n = 10
Source

Chronic Ethanol Differentially Modulates Glutamate Release from Dorsal and Ventral Prefrontal Cortical Inputs onto Rat Basolateral Amygdala Principal Neurons

eneuro, 2019

DOI 10.1523/eneuro.0132-19.2019 · PubMed 31548367 · PMC7070451, Fig. 6A3, A4

Licence: CC-BY-NC-SA-4.0

Named in the paper
“dmPFC” and “BLA principal neurons”
Made by
an AI model reading the paper (claude-opus-5, extract@0.3.0), 2026-10-10
Checked by

a second AI model (claude-opus-5) disagrees, 2026-10-10

“The dmPFC-evoked IPSCs are blocked by DNQX, indicating a polysynaptic feedback circuit rather than an inhibitory dmPFC connection.”

Status

proposed

Drafted and checked by AI models; it stays proposed until people have audited a sample of such claims.