Mouse

AI (Agranular insular area) projects to ACB (Nucleus accumbens)

2 claims from 1 source: 2 found, 0 tested and absent, 0 ambiguous. Evidence: anterograde tracer, retrograde tracer.

The claims behind it

clm-4gtpkt2zmdpresentretrograde tracerproposed

Retrograde virus injected into the nucleus accumbens labelled a distinct set of insular cortex neurons, concentrated in layer 5 with additional cells in layer 6, with little overlap with amygdala-projecting IC neurons.

DOI 10.1038/s41467-022-33241-9 · PubMed 36130959 · PMC9492683, Supplementary Fig. 5a–e

Made by an AI model reading the paper (claude-opus-5, extract@0.3.0); a second AI model (claude-opus-5) agrees.

clm-5hkgmkzmccpresentanterograde tracerproposed

Synaptophysin-tdTomato labelling of IC neurons tagged during extinction learning revealed axonal boutons preferentially in the nucleus accumbens rather than the central amygdala.

DOI 10.1038/s41467-022-33241-9 · PubMed 36130959 · PMC9492683, Fig. 3g–i; Supplementary Fig. 4

Made by an AI model reading the paper (claude-opus-5, extract@0.3.0); a second AI model (claude-opus-5) agrees.